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. 2013 Feb 22;2(1):e005066. doi: 10.1161/JAHA.112.005066

Table 4.

Correlation Between Cholesterol Homeostasis Markers and CVD Risk Factors*

Variable Women Men
Age BMI LDL‐C HDL‐C Non–HDL‐C TG* Age BMI LDL‐C HDL‐C Non–HDL‐C TG
Cholesterol synthesis markers*
Squalene −0.14* −0.06* −0.13* 0.02 −0.12* −0.04 −0.16* 0.03 −0.10* −0.09* −0.04 0.07*
Desmosterol 0.11* 0.06* −0.07* −0.03 −0.07* −0.03 0.19* 0.06 −0.17* 0.02 −0.18* −0.08*
Lathosterol 0.07* 0.08* −0.08* 0.02 −0.08* −0.04 0.11* 0.02 −0.10* −0.05 −0.06* 0.07*
Cholesterol absorption markers*
Campesterol −0.12* −0.23* −0.01 0.14* −0.09* −0.26* −0.21* −0.15* 0.02 0.10* −0.04 −0.19*
Sitosterol −0.12* −0.30* −0.03 0.14* −0.12* −0.31* −0.17* −0.20* 0.03 0.11* −0.04 −0.19*
Cholestanol −0.02 0.03 −0.31* −0.04 −0.30* −0.10* −0.01 0.01 −0.27* −0.07* −0.28* −0.08*
Cholesterol synthesis:absorption ratio*
Lathosterol:campesterol 0.13* 0.22* −0.04 −0.09* 0.01 0.16* 0.22* 0.12* −0.08* −0.10* −0.01 0.18*
Lathosterol:sitosterol 0.13* 0.26* −0.02 −0.08* 0.04 0.19* 0.19* 0.15* −0.09* −0.11* −0.01 0.18*
Lathosterol:cholestanol 0.07* 0.04 0.17* 0.04 0.15* 0.03 0.09* 0.003 0.11* 0.01 0.14* 0.11*

CVD indicates cardiovascular disease; BMI, body mass index; LDL‐C, LDL cholesterol; HDL‐C, HDL cholesterol; TG, triglycerides.

*

Pearson product moment correlation coefficient.

*

Triglycerides and cholesterol synthesis and absorption markers and ratios were log‐transformed during analysis to correct for their skewed distributions.

*

P<0.05; §P<0.01; P<0.001.