Table 4.
Descriptive Statistics/Results From Conditional Logistic Regression Analysis of Familial Risk of AF/AFl in the Swedish Population (1987–2008): Parents of Probands (Data Set I)
| Cases | Controls | OR (95% CI) for AF/AFl in 1 Parent | OR (95% CI) for AF/AFl in Both Parents | ||||||
|---|---|---|---|---|---|---|---|---|---|
| No. | Mean Age at Diagnosis, y (SD)* | AF/AFl in 1 Parent, %* | AF/AFl in Both Parents, %* | No. | AF/AFl in 1 Parent, %* | AF/AFl in Both Parents, %* | |||
| All | 32 464* | 52 (13) | 7338 (22.6) | 640 (2.0) | 162 320 | 22 013 (13.6) | 1065 (0.7) | 1.95 (1.89–2.00) | 3.60 (3.30–3.92)* |
| Males | 23 875 | 51 (13) | 5425 (22.7) | 496 (2.1) | 119 375 | 16 207 (13.6) | 768 (0.6) | 1.96 (1.90–2.02) | 3.87 (3.51–4.27) |
| Females | 8589 | 54 (13) | 1913 (22.3) | 145 (1.7) | 42 945 | 5806 (13.5) | 297 (0.7) | 1.91 (1.81–2.01) | 2.89 (2.43–3.44) |
| Age ≤49 y | 11 764 | 38 (9) | 2678 (22.8) | 248 (2.1) | 58 820 | 6983 (11.9) | 311 (0.5) | 2.33 (2.23–2.44) | 5.04 (4.36–5.82) |
| Age 50+ y | 20 700 | 60 (6) | 4660 (22.5) | 392 (1.9) | 103 500 | 15 030 (14.5) | 754 (0.7) | 1.77 (1.71–1.83) | 3.03 (2.72–3.37) |
AF/AFI indicates atrial fibrillation/atrial flutter.
*
The age is the same for cases and controls.
*
Number and percentage of cases and controls who have a parental history (1 or both) of AF/AFl, respectively.
*
61.8% of cases had >1 AF/AFl diagnosis.
*
OR for both parents with AF/AFl vs 1 parent with AF/AFl=1.85 (95% CI 1.69–2.02).