Table 6.
Cases | Controls | AF/AFl in ≥1 Sibling, %* | OR (95% CI) for AF/AFl in ≥1 Sibling | |||
---|---|---|---|---|---|---|
No. | Mean Age at Diagnosis, y (SD)* | AF/AFl in ≥1 Sibling, %* | No. | |||
All | 56 085* | 57 (11) | 8247 (14.7) | 280 425 | 15 763 (5.6) | 3.08 (3.00–3.16) |
Males | 39 648 | 56 (11) | 5555 (14.0) | 198 240 | 10 794 (5.4) | 3.01 (2.92–3.11) |
Females | 16 437 | 59 (11) | 2692 (16.4) | 82 185 | 4969 (6.1) | 3.23 (3.09–3.38) |
Age ≤49 y | 12 125 | 39 (9) | 986 (8.1) | 60 625 | 1412 (2.3) | 4.08 (3.79–4.41) |
Age 50+ y | 43 960 | 61 (6) | 7261 (16.5) | 219 800 | 14 351 (6.5) | 2.98 (2.90–3.06) |
AF/AFI indicates atrial fibrillation/atrial flutter.
The age is the same for cases and controls.
Number and percentage of cases and controls who have a sibling history (≥1 affected sibling) of AF/AFl, respectively.
63.7% of cases had >1 AF/AFl diagnosis.