Table 7.
Descriptive Statistics/Results From Conditional Logistic Regression Analysis of AF/AFl in the Swedish Population (1987–2008): Siblings in Families With ≥3 Siblings (Data Set III)
| Cases | Controls | OR (95% CI) for AF/AFl in 1 Sibling | OR (95% CI) for AF/AFl in ≥2 Siblings | ||||||
|---|---|---|---|---|---|---|---|---|---|
| No. | Mean Age at Diagnosis, y (SD)* | AF/AFl in 1 Sibling, %* | AF/AFl in ≥2 Siblings, %* | No. | AF/AFl in 1 Sibling, %* | AF/AFl in ≥2 Siblings, %* | |||
| All | 30 691 | 57 (11) | 4970 (16.2) | 897 (2.9) | 153 455 | 10 753 (7.0) | 986 (0.6) | 2.78 (2.69–2.87) | 5.72 (5.28–6.19)* |
| Males | 21 584 | 56 (11) | 3377 (15.7) | 546 (2.5) | 107 920 | 7374 (6.8) | 656 (0.6) | 2.73 (2.62–2.84) | 5.17 (4.69–5.71) |
| Females | 9107 | 59 (11) | 1593 (17.5) | 351 (3.9) | 45 535 | 3379 (7.4) | 330 (0.7) | 2.89 (2.73–3.06) | 6.88 (6.02–7.85) |
| Age ≤49 y | 6360 | 40 (10) | 661 (10.4) | 91 (1.4) | 31 800 | 1027 (3.2) | 72 (0.2) | 3.85 (3.51–4.21) | 8.51 (6.49–11.15) |
| Age 50+ y | 24 331 | 61 (6) | 4309 (17.7) | 806 (3.3) | 121 655 | 9726 (8.0) | 914 (0.8) | 2.66 (2.57–2.75) | 5.49 (5.06–5.97) |
AF/AFI indicates atrial fibrillation/atrial flutter.
*
The age is the same for cases and controls.
*
Number and percentage of cases and controls who have a sibling (1 or ≥2 affected siblings) history of AF/AFl, respectively.
*
OR for 2 siblings with AF/AFl vs 1 sibling with AF/AFl=2.06 (95% CI 1.89–2.24).