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. 2013 Feb 22;2(1):e000034. doi: 10.1161/JAHA.112.000034

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© 2013 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley-Blackwell.

This is an Open Access article under the terms of the Creative Commons Attribution Noncommercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Figure 5. — Transmission electron microscopy of collagen structure in ascending aortas. Nondilated (Non‐dil) aortas from patients with BAV (A) and TAV (B); dilated (Dil) aortas of patients with BAV (C) and TAV (D). Images represent overview, collagen fibers, and cross‐sectioned fibers. Bars are 5 μm, 200 nm, and 100 nm, respectively. Representative photomicrographs from a total of 4 patients are shown. E and F, Quantification of fibril diameters; 100 randomly selected fibrils from 4 patients were measured. ***P<0.001. BAV indicates bicuspid aortic valve; TAV, tricuspid aortic valve.