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. 2013 Feb 22;2(1):e000034. doi: 10.1161/JAHA.112.000034

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© 2013 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley-Blackwell.

This is an Open Access article under the terms of the Creative Commons Attribution Noncommercial License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Figure 7. — Decreased PLOD1 expression in dilated aortas of BAV patients. A, mRNA expression of PLOD1 in intima‐media of ascending aortas from patients with BAV and TAV. BAV nondilated (Non‐dil), n=24; BAV dilated (Dil), n=45; TAV nondilated, n=17; TAV dilated, n=23. *P<0.05, ***P<0.001 after adjustment for age. B, PLOD1 expression in media region of dilated ascending aortas from BAV (n=3) and TAV (n=3). C, Western blot of PLOD1 using protein extracts from dilated ascending aortas from BAV (N=4) and TAV (N=5). Arrow denotes PLOD1 protein with molecular weight of 83 kDa; broken arrow shows upregulated band of lower molecular weight. BAV indicates bicuspid aortic valve; TAV, tricuspid aortic valve.