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. Author manuscript; available in PMC: 2013 Mar 20.
Published in final edited form as: Exp Brain Res. 2009 Jun 17;196(4):545–556. doi: 10.1007/s00221-009-1885-3

Figure 4.

Figure 4

CART peptide immunoreaction in nuclei of amygdala (A and B), in various areas of the temporal archicortex (C–F) and in the somatosensory cortex (G and H) of a lean LETO (A, C, E and G) and an OLETF rat (B, D, F and H). A and B: Large number of CART peptide-immunoreactive neurons and fibers are visible in central nuclei of amygdala (CEA), but density of fibers is moderate in the medial nucleus (MEA) both in LETO (A) and OLETF rats (B). In the rostral part of basolateral amygdala nuclei (BLA) CART-immunoreactive fibers are less dense in the OLETF than in the LETO rat. C and D: CART peptide-immunoreactive granule cells (arrows), dendritic and axonal processes (arrowheads) are visible in the granule cell layer (g) and hilus (h) of the dentate gyrus in both strains. E and F: CART peptide-immunoreactive neurons in the subicular complex (SUB, arrows) and in islets of the entorhinal cortex (ENT, open arrows) in both LETO (E) and OLETF (F) rats. G and H: A large number of faintly immunoreactive neurons was found in layer IV of the somatosensory cortex in both LETO (G) and OLETF (H). Antero-posterior coordinates are represented in mm distance from the Bregma (Br). Additional abbreviations: DG, dentate gyrus; m, molecular layer of the dentate gyrus; CA1, CA1 region of Ammon’s horn. Scale bars = 100 μm in C, D, G, H, 200 μm in A and B, 500 μm in E and F.