Table 3.

Summary of F_ST for Outlier SNPs (fig. 5).

SNP Name	SNP Origina	Associated Gene	MND	MN	MD	ND	G5	LabMet
Aln101510_393	Recent	Transforming growth factor, beta 2	0.959	0.960	0.936	−0.032	0.948	0.072
Aln102749_378	Old	Glutamate receptor, ionotrophic, AMPA 4	0.933	−0.001	1	0.981	0.879	—
Aln102504_1609	Old	Iroquois homeobox protein 1, b	0.931	0.933	1	−0.033	1	—
Aln113666_686	Old	Dicer 1, ribonuclease type III	0.905	0.927	0.565	0.768	0.986	0.001
Aln110417_383	Recent	Neuroligin 1	0.870	0.881	0.262	0.770	0.909	—
Aln105577_385	Recent	TOX high mobility group box family member 3	0.840	—	0.945	0.950	1	—
Aln103506_276	Recent	Pre-B-cell leukemia homeobox 3	0.840	—	0.945	0.950	1	—
Aln103131_1413	Old	NA	0.830	0.834	−0.025	0.770	0.769	0.072
Aln102321_608	Old	Zic family member 1 (odd-paired homolog, Drosophila)	0.794	—	0.927	0.933	0.917	—
Aln118947_983	Recent	Tubulin folding cofactor D	0.794	—	0.927	0.933	0.917	—
Aln104822_926	Old	Solute carrier family 4, anion exchanger, member 1	0.777	0.812	0.852	0.210	0.782	—
Aln101222_933	Recent	Serine palmitoyltransferase, long chain base subunit 3	0.745	—	0.905	0.914	0.835	—
Aln112709_570	Old	CUB and Sushi multiple domains 2	0.718	0.720	0.809	0.033	0.723	0.275
Aln100532_2174	Old	Potassium channel, subfamily K, member 9	0.691	—	0.880	0.891	0.741	—
Aln109969_676	Recent	Homeobox A10	0.626	0.635	—	0.484	0.566	—
Aln105584_365	Old	Cathepsin A	0.622	0.634	0.459	−0.032	0.668	0.817
Aln106343_852	Recent	Homeobox B9	0.599	0.618	0.260	0.403	0.707	—
Aln103262_483	Old	Chromodomain helicase DNA-binding protein 4	0.649	0.613	0.240	0.979	0.542	0.064
Aln112165_601	Old	NA	0.600	0.611	0.440	−0.032	0.586	0.316
Aln100281_1741	Old	Patched 1	0.592	0.598	0.588	−0.004	0.728	0.914
Aln102003_434	Old	Thrombospondin, type I, domain containing 7 A	0.562	0.034	0.943	0.809	0.956	—
Aln104744_1075	Old	POU class 3 homeobox 3	0.559	0.542	0.874	0.175	0.570	−0.019
Aln110178_952	Old	ATPase, Na+/K+ transporting, alpha 2 polypeptide	0.273	0.087	0.853	0.481	0.517	—
Aln102499_612	Recent	PRKC, apoptosis, WT1, regulator	0.636	—	0.851	0.864	0.659	—
Aln113582_375	Old	Membrane frizzled-related protein	0.271	0.042	0.815	0.514	0.454	—
Aln102027_539	Old	Calcium channel, voltage-dependent, P/Q type, alpha 1 A subunit	0.236	0.249	0.097	—	1	1
Aln105956_1118	Recent	Carbonyl reductase 1	0.498	0.511	0.324	—	0.699	0.973
Aln101293_1168	Old	Membrane protein, palmitoylated 2	0.080	0.021	0.257	0.408	0.425	0.946
csrp1	Recent	Cysteine and glycine-rich protein 1	0.348	0.361	0.188	—	0.783	0.946
Aln107567_398	Old	NA	0.376	0.390	0.213	—	0.878	0.945
Rhodopsin	Old	Rhodopsin	0.420	0.376	0.204	0.848	0.666	0.944
Aln103439_528	Recent	NA	0.378	0.392	0.217	—	0.633	0.868
Aln122064_679	Old	Aquaporin 3 (Gill blood group)	0.451	0.463	0.285	−0.037	0.717	0.860

Note.—Underlined F_ST values are significantly elevated outliers (P < 0.05) of the empirical distribution.

^aSNP origin defined as recent if polymorphism is present only in Lake Malawi or old if polymorphism is shared with lineages outside Lake Malawi.