Table III.

Association of clinical factors with key mediators

	IL-6		IL-8		Leptin		TNF-α		MCP-1		Adiponectin		Resistin		PAI-1
	Beta	P	Beta	P	Beta	P	Beta	P	Beta	P	Beta	P	Beta	P	Beta	P
Age	−0.5493	0.026	−0.5352	0.035	−0.2006	0.372	−0.6250	0.005	−0.3297	0.183	−0.3731	0.125	−0.1896	0.332	−0.2620	0.253
Sex	0.0690	0.707	0.0924	0.626	−0.2169	0.220	−0.1052	0.515	−0.2822	0.146	−0.4319	0.027	−0.1623	0.289	−0.0589	0.739
Race	0.0289	0.875	0.0450	0.812	0.1473	0.402	0.1710	0.295	0.1210	0.527	0.1535	0.413	0.0379	0.803	−0.0216	0.903
BMI	−0.3552	0.173	−0.3481	0.194	0.0339	0.889	−0.2535	0.265	0.2011	0.450	−0.1887	0.468	−0.0486	0.818	−0.2070	0.404
DM	0.2352	0.574	0.1865	0.664	0.3793	0.342	0.4276	0.249	0.3745	0.389	0.7117	0.101	0.4364	0.211	0.3907	0.335
HTN	0.2330	0.308	0.2233	0.342	0.0110	0.959	0.2196	0.274	0.1506	0.521	0.1023	0.655	0.1061	0.570	0.4666	0.040
HLP	−0.2685	0.228	−0.2693	0.240	−0.5246	0.018	−0.5273	0.011	−0.1352	0.553	−0.5118	0.028	−0.3929	0.038	−0.2263	0.290
CAD	0.3750	0.188	0.3240	0.267	0.3074	0.253	0.3134	0.209	0.1522	0.600	−0.0232	0.935	0.2856	0.222	0.4660	0.093
CHF	0.1901	0.320	0.1684	0.391	−0.0891	0.621	0.3355	0.052	0.2423	0.223	0.2862	0.143	0.4042	0.015	0.3916	0.040
CVA	0.1534	0.514	0.0996	0.680	−0.0317	0.886	0.2485	0.233	0.3736	0.132	0.2975	0.216	0.4245	0.035	0.2936	0.200
Renal Disease	0.6544	0.012	0.6397	0.016	−0.1370	0.554	0.5954	0.009	0.3900	0.130	−0.2392	0.335	0.4185	0.045	0.4599	0.058
Pulm Disease	0.2209	0.268	0.2511	0.223	−0.0043	0.982	0.1392	0.424	−0.1173	0.566	−0.0880	0.659	0.0474	0.770	−0.2469	0.200
Smoking	−0.0982	0.624	−0.0901	0.662	0.1484	0.436	0.0745	0.671	0.0324	0.875	0.3241	0.117	−0.1225	0.459	−0.0448	0.816
Anti-platelet	0.3378	0.340	0.3912	0.284	0.5417	0.113	0.3686	0.238	−0.4758	0.198	0.2229	0.531	−0.0453	0.875	−0.2551	0.453
Warfarin	0.2766	0.329	0.3456	0.238	0.1741	0.515	0.1569	0.526	−0.5937	0.049	−0.2723	0.342	−0.3393	0.151	−0.2787	0.307
CaCh Blocker	−0.2986	0.176	−0.2977	0.190	−0.1556	0.452	−0.3845	0.052	−0.4506	0.053	0.2417	0.276	−0.3079	0.094	−0.3102	0.146
Beta Blocker	−0.1512	0.674	−0.2131	0.565	0.4604	0.184	0.3163	0.320	0.7397	0.055	0.6435	0.085	0.4028	0.180	0.1861	0.591
ACEI/ARB	−0.2358	0.312	−0.2417	0.314	0.1683	0.444	−0.2268	0.269	−0.2520	0.296	−0.2112	0.369	−0.0236	0.901	−0.4384	0.057
Statin	0.3828	0.165	0.4015	0.157	0.1987	0.440	0.4878	0.048	0.2543	0.366	0.2667	0.333	−0.0132	0.953	0.1342	0.606
Insulin	−0.5661	0.278	−0.4999	0.350	−0.9100	0.072	−1.1788	0.014	−0.8871	0.105	−1.1738	0.032	−0.6214	0.152	−0.8692	0.089
Steroid	−0.1145	0.553	−0.1072	0.589	0.0584	0.749	0.0183	0.914	0.1123	0.574	0.1713	0.382	0.0823	0.604	0.0234	0.899
Amputation	−0.2700	0.477	−0.2247	0.564	−0.2757	0.444	−0.3099	0.354	−0.2957	0.452	−0.5031	0.195	−0.2078	0.506	−0.2015	0.580
NSAID	0.1562	0.582	0.1114	0.703	−0.5404	0.053	0.0489	0.844	0.3257	0.272	−0.0756	0.792	0.1797	0.443	0.3785	0.173