Table 1. Baseline Characteristics at Listing.
| Variable | Category | Prospective crossmatch required at listing | p-value | ||
|---|---|---|---|---|---|
|
| |||||
| Cohort (N = 6343) | No (n = 5,855; 92%) | Yes (n = 488; 8%) | |||
| Age | 5.5 ± 6.1 | 5.4 ± 6.1 | 6.4 ± 6.2 | 0.0011 | |
| Gender | Female | 2,771 (43.7%) | 2,564 (43.8%) | 207 (42.4%) | 0.557 |
| Race/ethnicity | White | 3,732 (58.8%) | 3,453 (59.0%) | 279 (57.2%) | 0.159 |
| Black | 1,246 (19.6%) | 1,134 (19.4%) | 112 (23.0%) | · | |
| Hispanic | 1,052 (16.6%) | 982 (16.8%) | 70 (14.3%) | — | |
| Other | 313 (4.9%) | 286 (4.9%) | 27 (5.5%) | — | |
| Diagnosis | CHD | 3,094 (48.8%) | 2,659 (47.6%) | 435 (57.9%) | <0.0001 |
| DCM | 2,498 (39.4%) | 2,248 (40.2%) | 250 (33.3%) | — | |
| RCM/HCM | 468 (7.4%) | 445 (8.0%) | 23 (3.1%) | — | |
| Retransplant | 174 (2.7%) | 141 (2.5%) | 33 (4.4%) | — | |
| Other | 87 (1.4%) | 79 (1.4%) | 8 (1.1%) | — | |
| Unknown | 22 (0.3%) | 20 (0.4%) | 2 (0.3%) | — | |
| Primary payer | Public/gov’t insurance | 2,724 (43.1%)a | 2,519 (43.2%) | 205 (42.0%) | 0.237 |
| Private insurance | 3,425 (54.1%) | 3,151 (54.0%) | 274 (56.2%) | — | |
| Donation | 93 (1.5%) | 88 (1.5%) | 5 (1.0%) | — | |
| Free care | 9 (0.1%) | 7 (0.1%) | 2 (0.4%) | — | |
| None | 16 (0.3%) | 16 (0.3%) | 2 (0.4%) | — | |
| Other | 59 (0.9%) | 57 (1.0%) | 3 (0.4%) | — | |
| History of a prior Tx UNOS status | Yes | 194 (3.1%) | 165 (2.8%) | 29 (5.9%) | <0.0001 |
| 1 | 1,092 (17.2%) | 1,034 (17.7%) | 87 (11.6%) | 0.002 | |
| 1A | 2,937 (46.3%) | 2,707 (46.2%) | 230 (47.1%) | — | |
| 1B | 613 (9.7%) | 549 (9.4%) | 64 (13.1%) | — | |
| 2 | 1,661 (26.2%) | 1,530 (26.1%) | 131 (26.8%) | — | |
| 7 | 40 (0.6%) | 35 (0.6%) | 5 (1.0%) | — | |
| UNOS status (grouped) | 1/1A/1B | 4,642 (73.2%) | 4,290 (73.3%) | 352 (72.1%) | 0.585 |
| 2/7 | 1,701 (26.8%) | 1,565 (26.7%) | 136 (27.9%) | — | |
| Inotropic support | Yes | 3,104 (48.9%) | 2,867 (49.0%) | 237 (48.6%) | 0.865 |
| Ventilatory support | Yes | 1,712 (27.0%) | 1,593 (27.2%) | 119 (24.4%) | 0.177 |
| ECMO | Yes | 668 (10.5%) | 614 (10.5%) | 54 (11.1%) | 0.689 |
| VAD | Yes | 277 (6.2%)b | 244 (6.0%) | 33 (9.0%) | 0.022 |
Bold indicates statistical significance. ECMO, extracorporeal membrane oxygenation; Tx, transplantation; UNOS, United Network for Organ Sharing; VAD, ventricular assist device.
a
n = 6,326;
b
n = 4,456.