Table 3. Multivariable Model of Death After Transplantation.
| Variable | Hazard ratio (95% CI) | p-value |
|---|---|---|
| Prospective crossmatch required | 1.04 (0.87–1.25) | 0.670 |
| Agea (years) | ||
| 1–10 | 0.92 (0.79–1.07) | 0.259 |
| 11–17 | 1.47 (1.26–1.71) | <0.0001 |
| Gender (male) | 0.88 (0.78–0.98) | 0.019 |
| Raceb | ||
| Black | 1.84 (1.62–2.10) | <0.0001 |
| Hispanic | 1.06 (0.90–1.25) | 0.510 |
| Other | 1.04 (0.78–1.38) | 0.802 |
| Listing diagnosis of CHD | 1.49 (1.32–1.68) | <0.0001 |
| History of prior heart transplant | 1.76 (1.36–2.28) | <0.0001 |
| Status 1/1A/1Bc | 0.91 (0.77–1.07) | 0.249 |
| Inotropes | 1.08 (0.95–1.23) | 0.232 |
| Ventilator | 1.34 (1.14–1.56) | 0.0003 |
| ECMO | 1.89 (1.53–2.34) | <0.0001 |
| Ischemic time (hours) | 1.02 (0.98–1.07) | 0.307 |
| Donor:recipient gender mismatch | 1.04 (0.93–1.16) | 0.461 |
| Positive donor-specific crossmatchd | 1.24 (1.06–1.46) | 0.009 |
| Unknown donor- specific crossmatchd | 1.15 (1.01–1.32) | 0.042 |
All variables pertain to time of transplant. Bold indicates statistical significance. CHD, congenital heart disease; ECMO, extracorporeal membrane oxygenation.
Versus age < 1 year;
versus white;
versus Statuses 2 and 7;
versus negative donor-specific crossmatch.