Table 3.
Sulforaphane pretreatment delays graft rejection.
| WT day 2 (grade N/total N) |
KO day 2 (grade N/total N) |
WT + SF day 2 (grade N/total N) |
WT day 5 (grade N/total N) |
KO day 5 (grade N/total N) |
WT + SF day 5 (grade N/total N) |
|
|---|---|---|---|---|---|---|
| No rejection | 1/5 | 2/3 | 5/5 | |||
| Grade 1R | 1/5 | 1/3 | 1/4 | 1/4 | ||
| Grade 2R | 3/5 | 3/4 | 3/4 | 3/3 | ||
| Quilty | 4/4 |
N = 3–5 animals for each group. Data is displayed as “N”—meeting histological criteria/total analyzed “N.” Heart sections were formalin fixed and paraffin embedded prior to being stained with H&E for histology analysis. Definition of terms: 1R = mild, focal perivascular and/or interstitial infiltrate without myocyte damage, 2R = medium, multifocal infiltrate with myocyte damage, “Quilty”: inflammation from the outside-in, that is, starting from the epicardium, possibly due to infection rather than rejection.