Table 1. Fecal organic acid and short chain fatty acid concentration of twins discordant and concordant for BMI.
Component | Lower BMI siblings (n=16) (mean±s.d.e) | Higher BMI siblings (n=16) (mean±s.d.e.) | P-value | Controls (n=32) (mean±s.d.e.) |
---|---|---|---|---|
Acetate | 56.44±6.38 | 74.41±9.04 | 0.252 | 56.97±6.49 |
Butyrate | 13.76±1.59 | 25.12±3.51 | 0.013 | 16.40±1.90 |
Iso-butyrate | 0.23±0.14 | 1.15±0.33 | 0.067 | 1.09±0.29 |
Malate | 10.56±2.60 | 25.71±8.3 | 0.403 | 11.81±2.84 |
Propionate | 16.82±1.76 | 25.25±4.04 | 0.193 | 15.86±1.42 |
Succinate | 0.64±0.35 | 0.03±0.03 | 0.178 | 1.41±1.21 |
Valerate | 1.47±0.30 | 3.43±0.62 | 0.006 | 2.00±0.30 |
Abbreviation: BMI, body mass index.
Citrate, lactate, fumarate and formate were not detected. Statistical testing of between the concentrations of lower BMI sibling and higher BMI sibling groups was performed with paired dependent two-group Wilcoxon signed rank tests and P-values are reported (significant P-values are in bold).