Table 1.
Baseline demographic, anthropometrical, endothelial function and biochemical characteristics of the general population.
| Variable | Global | AGE-placebo Group (n = 20) |
Placebo-AGE group (n = 23) |
P value |
|---|---|---|---|---|
| Age (years) | 40.79 (10.71) | 44.75 (10.5) | 37.34 (9.8) | 0.02∗,Ψ |
| SBP (mm Hg) | 123.73 (15.63) | 127 (15) | 120 (15) | 0.15* |
| DBP (mm Hg) | 81.59 (10.86) | 82 (12) | 80 (9) | 0.56* |
| BMI (kg/m2) | 33.07 (5.01) | 33.7 (5.4) | 32.5 (4.5) | 0.54* |
| WC (cm) | 100.44 (10.32) | 102.4 (11.6) | 98.7 (8.8) | 0.23* |
| HC (cm) | 109.42 (8.89) | 108.8 (8.4) | 109.8 (9.4) | 0.46* |
| Glucose (mg/dL) | 87.12 (14.99) | 91.85 (17.53) | 83 (11.19) | 0.10* |
| Cholesterol (mg/dL) | 198.61 (30.82) | 201.9 (36.61) | 195.73 (25.24) | 0.51* |
| LDL (mg/dL) | 116.96 (28.16) | 119.25 (35.10) | 114.95 (20.98) | 0.61* |
| HDL (mg/dL) | 37.47 (5.68) | 37.51 (6.55) | 37.42 (4.94) | 0.87* |
| TAG (mg/dL) | 220.91 (71.96) | 225.65 (80.07) | 216.78 (65.65) | 0.88# |
| CRP (mg/L) | 5.79 (4.73) | 7.04 (5.73) | 4.70 (3.39) | 0.21* |
| IL-6 (units/mL) | 1.97 (0.88) | 1.93 (0.87) | 2.00 (0.90) | 0.68* |
| Adiponectin (ng/mL) | 5936.56 (1813.74) | 5516.7 (1665.24) | 6301.65 (1893.59) | 0.15* |
| Leptin (ng/mL) | 26.19 (19.28) | 27.29 (18.64) | 25.22 (20.17) | 0.60# |
| Insulin (μU/mL) | 22.26 (25.87) | 28.81 (36.07) | 16.58 (9.03) | 0.10# |
| HOMA index | 5.04 (6.51) | 6.82 (9.03) | 3.49 (2.22) | 0.05# |
| FMV (%) | 11.06 (5.98) | 10.68 (5.39) | 11.38 (6.37) | 0.70* |
SBP: systolic blood pressure; DBP: diastolic blood pressure; BMI: body mass index; WC: waist circumference; HC: hip circumference, LDL-C: low density lipoprotein cholesterol; HDL-C: high density lipoprotein cholesterol; TG: triglycerides; CRP: C-reactive protein; IL-6: interleukin-6; FMV: flow-mediated vasodilatation. Values are expressed as mean ± SD. *AGE group versus placebo group with independent Student's t-test. #AGE group versus placebo group with Wilcoxon signed-ranks test. Ψ P < 0.05.