Table 3.

First-line chemotherapy regimens in metastatic seminoma and non-seminoma

BEP	(repeat cycles every 3 weeks)a		reference [97]
Cisplatin	20 mg/m2	Day 1–5
Etoposide	100 mg/m2	Day 1–5
Bleomycin	30 mg	Day 1, 8, 15
EP	(repeat cycles every 3 weeks)b		reference [33]
Cisplatin	20 mg/m2	Day 1–5
Etoposide	100 mg/m2	Day 1–5
VIP	(repeat cycles every 3 weeks)c		reference [98]
Cisplatin	20 mg/m2	Day 1–5
Etoposide	75 mg/m2	Day 1–5
Ifosfamide	1,2 g	Day 1–5

^aThree cycles BEP in IGCCCG ‘good prognosis’ patients; four cycles BEP in IGCCCG ‘intermediate prognosis’ and ‘poor prognosis’ patients.

^bFour cycles EP only in IGCCCG ‘good prognosis’ patients with contraindications to bleomycin.

^cFour cycles VIP only in IGCCCG ‘intermediate risk‘ and ‘poor risk’ patients with contraindications to bleomycin.

VIP, cisplatin, etoposide and ifosfamide.