Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Dec;2(12):120138. doi: 10.1098/rsob.120138

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2012 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/, which permits unrestricted use, provided the original author and source are credited.

PMC Copyright notice

Figure 3. — RAD, shown in yellow, bound within the N-terminal domain of the yeast Hsp90 (PDB ID: 1BGQ). Hsp90 residues forming the binding site of this antibiotic molecule are shown in blue. Indicated in brown is the conserved leucine residue that is altered to an isoleucine in the Hsp90 of Humicola fuscoatra, thus generating partial RAD resistance [60]. Indicated in magenta is the conserved methionine (Met84) that is altered to phenylalanine in Hsp90 of the maize pathogen Colletotrichum graminicola.