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. 2013 Jan 1;126(1):234–243. doi: 10.1242/jcs.113795

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© 2013. Published by The Company of Biologists Ltd

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Fig. 5. — Increased BMP signaling and altered chondrocyte differentiation in Jab1^flox/flox; Col2a1-Cre mutant chondrocytes. Real-time qualitative RT-PCR assay for BMP signaling components and chondrocyte differentiation markers in primary chondrocytes from E18.5 Jab1^flox/flox; Col2a1-Cre mutants. The data represent the mean ± s.d. from 3–5 mice per genotype. MUT, Jab1^flox/flox; Col2a1-Cre mutants; WT, wild-type littermates. The gene expression changes in some cases were not statistically significant with large SD, likely due to the heterogeneity of each mouse embryo sample and also the limited numbers of Jab1 cKO mutant samples analyzed.