Table 7.
Colon | Period | Experimental group compared | ||||
---|---|---|---|---|---|---|
with untreated control rats | ||||||
Gene | DSS | BE | Cuo | To | Ro | |
Phase 1 | — | ↔ | ↔ | ↔ | ↔ | |
Nrf2 | Phase 2 | ↓ | ↓ | ↔ | ↓ | ↓ |
Phase 3 | ↔ | ↔ | ↔ | ↔ | ↔ | |
Phase 1 | — | ↔ | ↔ | ↔ | ↑ | |
Keap1 | Phase 2 | ↔ | ↔ | ↔ | ↔ | ↔ |
Phase 3 | ↔ | ↔ | ↔ | ↔ | ↔ | |
Phase 1 | — | ↔ | ↔ | ↔ | ↔ | |
HO1 | Phase 2 | ↔ | ↔ | ↔ | ↔ | ↔ |
Phase 3 | ↔ | ↔ | ↔ | ↑ | ↔ | |
Phase 1 | — | ↔ | ↔ | ↔ | ↔ | |
NQO1 | Phase 2 | ↔ | ↔ | ↔ | ↓ | ↔ |
Phase 3 | ↔ | ↔ | ↔ | ↔ | ↔ | |
Phase 1 | — | ↓ | ↔ | ↔ | ↔ | |
SOD1 | Phase 2 | ↔ | ↔ | ↔ | ↔ | ↔ |
Phase 3 | ↔ | ↔ | ↔ | ↔ | ↔ | |
Phase 1 | — | ↔ | ↔ | ↔ | ↑ | |
GPx2 | Phase 2 | ↔ | ↔ | ↑ | ↔ | ↔ |
Phase 3 | ↓ | ↓ | ↓ | ↓ | ↓ | |
Phase 1 | — | ↓ | ↔ | ↔ | ↑ | |
GSTK1 | Phase 2 | ↔ | ↔ | ↔ | ↓ | ↓ |
Phase 3 | ↔ | ↓ | ↓ | ↓ | ↓ | |
Phase 1 | — | ↔ | ↔ | ↔ | ↑ | |
GSTP1 | Phase 2 | ↔ | ↔ | ↔ | ↓ | ↔ |
Phase 3 | ↓ | ↓ | ↓ | ↓ | ↓ | |
Phase 1 | — | ↔ | ↑ | ↔ | ↑ | |
GSTT2 | Phase 2 | ↓ | ↓ | ↓ | ↓ | ↓ |
Phase 3 | ↔ | ↔ | ↔ | ↔ | ↔ |
Different arrows summarize the expression results: ↔: no effect, ↑: increase, and ↓: decrease. For statistically analyzed means ± SEM see Table 10.