TABLE 3.

HAZARD RATIOS OF CLINICAL WORSENING EVENTS ASSOCIATED WITH SOCIOECONOMIC STATUS TERTILES

	Socioeconomic Status Tertiles
Adjustment	Low (n = 73)	Middle (n = 90)	High (n = 99)	P for Trend
Events (n, %)	47 (64.4)	35 (38.9)	27 (27.3)
Model 1*	2.85 (1.75–4.65)	1.68 (1.00–2.80)	1.0	<0.001
Model 2†	2.37 (1.44–3.91)	1.68 (1.01–2.81)	1.0	0.003
Model 3‡	2.60 (1.56–4.35)	1.76 (1.04–2.96)	1.0	0.001

Data are presented as hazard ratio (95% confidence interval) unless otherwise stated. Clinical worsening was defined by the combined endpoint of death, lung transplantation, hospitalization, or the addition of or switch to other active therapies because of worsening pulmonary arterial hypertension or right heart failure.

^*Model 1: adjusted for age and sex.

^†Model 2: Model 1 plus adjustment for World Health Organization functional classification and pulmonary vascular resistance.

^‡Model 3: Model 2 plus adjustment for phosphodiesterase type 5 inhibitors, endothelin receptor antagonists and prostanoids.