Table 3.
Secondary outcomes.
| Outcome | Baseline | Mean difference ± SE (95% CI) | P value | 2 years | Mean difference ± SE (95% CI) |
P value | Time by treatment interaction (F; significance) |
|---|---|---|---|---|---|---|---|
| SF-36 PCS | |||||||
| Active | 51.9 ± 19.2 | 11.8 ± 7.0 | 67.6 ± 16.3 | 30.5 ± 5.6 | |||
| Control | 39.7 ± 17.8 | (−2.2, 25.8) | 0.1 | 37.1 ± 14.9 | (18.5, 42.6) | <0.001* | F = 5.8; P = 0.02 |
| SF-36 MCS | |||||||
| Active | 64.7 ± 19.6 | 14.1 ± 7.2 | 73.7 ± 13.1 | 16.9 ± 4.8 | |||
| Control | 50.3 ± 19.7 | (−0.5, 28.6) | 0.1 | 56.8 ± 12.5 | (7.2, 26.6) | <0.001* | F = 0.032; P = 0.86 |
| Knee Society Knee Score | |||||||
| Active | 58.1 ± 18.8 | 3.4 ± 6.8 | 77.8 ± 12.1 | 17.8 ± 4.7 | |||
| Control | 54.1 ± 16.3 | (−10.3, 17.2) | 0.6 | 60.0 ± 14.9 | (8.3, 27.3) | <0.001* | F = 4.3; P = 0.044 |
| Knee Society Function Score | |||||||
| Active | 57.1 ± 16.0 | 8.5 ± 6.5 | 74.6 ± 18.3 | 25.2 ± 6.9 | |||
| Control | 47.2 ± 16.4 | (−4.6, 21.7) | 0.2 | 49.4 ± 19.3 | (11.2, 39.0) | <0.001* | F = 6.5; P = 0.014 |
SF-36: Short Form 36 (SF-36).
*P ≤ 0.05 was considered statistically significant. Groups showed no significant differences at the baseline. Groups showed significant differences in all outcomes after two years. There was a significant difference in improvement over time between groups in all outcomes except for the SF-36 mental component summary (MCS).