Table 3.

Accepted Indications for ICD therapy in Familial Dilated Cardiomyopathy

Indication	ICD Recommendation*
Resuscitated sudden cardiac death from VF or VT	Class I
Sustained VT and significant LV dysfunction†	Class I
LVEF≤35% and class II–III heart failure on optimal medical therapy	Class I
Unexplained syncope and significant LV systolic dysfunction† with inducible VT/VF at EPS	Class I
Unexplained syncope and significant LV systolic dysfunction†	Class IIa
Sustained VT and normal or near normal LVEF	Class IIa
LVEF≤30–35% and class I heart failure on optimal medical therapy	Class IIb
Family history of sudden death	Class IIb
LV hypertrabeculation/Noncompaction	Class IIb

^*2008 AHA/ACC/HRS consensus guideline recommendations.

Class I: Should be performed; Class IIa: Reasonable to perform; Class IIb: May be considered. ICD therapy is not advised for patients without reasonable expectation of survival with good functional status for more than 1 year.

EPS = electrophysiological study.