Figure 7. Fluorescence emission spectra of drug-chitosan systems in 10 mM acetate buffer pH 6 at 25°C presented for (A) 4-hydroxytam-ch-15: (a) free 4-hydroxytam (30 µM), (b–h) with chitosan at 30, 40, 50, 60, 80, 100, 120 and 140 µM; (B) 4-hydroxytamx-chitosan-100: (a) free 4.hydroxytam (30 µM), (b–h) chitosan at 1, 3, 5, 7, 10, 15, 20 and 30 µM; (C) 4-hydroxytam-ch-200: (a) free 4-hydroxytam (30 ) (b–f) with chitosan at 3, 5, 7, 20 and 30 µM; Inset: K values calculated by F 0/(F 0 –F) vs 1/[chitosan] for A' (4-hydroxytam -chitosan-15), B' (4 hydroxytam – chitosan 100) and C' (4-hydroxytam -chitosan-200).
