Table 3. Changes in body-weight, leptin and gut hormones after surgery.
Final body-weight (g) | Change in body-weight (g) | Plasma leptinlevel (ng/ml) | Plasma acyl-ghrelin level (pmol/l) | Plasma total PYY level (pmol/l) | Plasma active-GLP1 level (pmol/l) | |
GBP surgery (n = 8) | 24.5 (1.2) | −11.4 (1.3) | 0.27 (0.07) | 1179 (258) | 29.0 (5.1) | 10.5 (2.9) |
Sham surgery (n = 7) | 31.1 (1.4) | −4.8 (0.6) | 1.05 (0.23) | 517 (83) | 13.1 (1.8) | 2.3 (0.4) |
GBS vs. Sham (P value) | 0.003* | 0.0007* | 0.004* | 0.03* | 0.01* | 0.02* |
GBP = modified gastric bypass surgery; data presented as Mean (Standard Error of Mean) or P value (t test).