Figure 6. Superimpose of binding orientation of NAD+ in SIRT2 active site.
a) WT with Q167A, deviation of N9A of adenine was 4.14 Å and b) WT and H187A deviation of N9A of adenine was 1.66 Å. WT-magenta, Q167A-green, and H187A-yellow.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.