Table 4. Prognostic value of biomarkers and echocardiographic parameters for cardiovascular events using c-statistic and ROC curve analysis with calculated AUCs.

Parameters	Cardiovascular events
	AUCs	Change in c-statistic
FRS	0.589
FRS + albumin	0.793	0.204
FRS + hemoglobin	0.768	0.179
FRS + eGFR	0.756	0.167
FRS + proteinuria	0.678	0.089
FRS + LA diameter >4.7 cm	0.725	0.136
FRS + LVH	0.700	0.111
FRS + LVEF <50%	0.648	0.059

Abbreviations: ROC, receiver operating characteristic; AUC, area under the curve; eGFR, estimated glomerular filtration rate; LA, left atrial; LVH, left ventricular hypertrophy; LVEF, left ventricular ejection fraction.