Skip to main content
. Author manuscript; available in PMC: 2014 Apr 15.
Published in final edited form as: Biochem Pharmacol. 2013 Feb 8;85(8):1195–1202. doi: 10.1016/j.bcp.2013.01.031

Fig. 2. Identification of the microsomal metabolites of PTI using LC-MS/MS analysis.

Fig. 2

MS (top) and MS2 (bottom) ion spectra were shown. A: Top, the protonated demethyl-PTI was observed at m/z 600.2. Bottom, the ion above was fragmented to generate ions at m/z 121.1 and 297.9. B: Top, the protonated debenzoyl-PTI was observed at m/z 476.5. Bottom, the ion above was fragmented to generate ions at m/z 120.9 and 173.7 C: Top, the protonated hydroxy-PTI was observed at m/z 630.5. Bottom, the ion above was fragmented to generate ions at m/z 138.4 and 311.4.