Table 3. MIC values for indicated microorganisms as determined by microdilution assay.
p4 (µg/ml) | E. coli ATCC 11775 | S. aureus ATCC 6538 | P. aerugin. ATCC 10145 | C. albicans ATCC 24433 | S. epiderm. ATCC 12228 | S. epiderm. ATCC 14990 |
100 | 100 | 100 | 100 | 100 | 100 | 100 |
50 | 100 | 100 | 100 | 100 | 100 | 100 |
25 | 100 | 100 | 100 | 100 | 100 | 100 |
12.5 | 100 | 100 | 100 | 100 | 100 | 100 |
6.3 | 100 | 98.9 | 100 | 100 | 99.7 | 99.1 |
3.1 | 100/98.6 | 72 | 99.4 | 80 | 96.8 | 97 |
1.6 | 92.1 | 57 | 96.7 | 39 | 83 | 84 |
0.8 | 82 | 23 | 71 | 18 | 61 | 38 |
0.4 | 57 | 11 | 23 | 7 | 16 | 34 |
0.2 | 16 | 0 | 6 | 14 | 17 | 17 |
0.1 | 20 | 0 | 17 | 0 | 8 | 8 |
0.05 | 7 | 0 | 0 | 0 | 0 | 0 |
0.02 | 26 | 0 | 0 | 0 | 0 | 0 |
0.01 | 0 | 0 | 0 | 0 | 0 | 0 |
MIC (µg/ml) | 3.1–6.3 | 12.5 | 6.3 | 6.3 | 12.5 | 12.5 |
Data in columns indicate % of killing for each strain. The MIC was defined as the lowest concentration of p4 showing no visible growth (100% of killing). Mean of at least 3 measurements is shown.