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. 2013 Mar 20;8(3):e59194. doi: 10.1371/journal.pone.0059194

Figure 5. The anti-HIV effects of IL-27 on DCs are not mediated by Type I IFNs.

Figure 5

A: iDCs from three independent donors were treated with or without IL-27 for 24 hours and then RNA was extracted. An Affymetrix microarray and gene expression profile analysis were performed as described in the Materials and Methods. B: HIV-infected iDCs were pretreated with anti-IFNαR antibody (R2Ab) or isotype control antibody (Ctrl Ab) before IL-27 treatment. As an assay control, the antibody-pretreated cells were also treated with IFN-α. This graph represents one donor from three independent donors. Error bars represent SD of replicates.