Table 3.
In Utero exposures and odds of an endometriosis diagnosis, The ENDO Study – sensitivity analyses.
| Exposures | Visualized & Histologically-Confirmed Endometriosis vs. No Endometriosis (n=473) | Endometriosis Stages 3–4 vs. No Endometriosis (n=339) | Endometriosis vs. Women with Postoperative Diagnosis of Normal Pelvis (n=320) |
|---|---|---|---|
| Adjusted OR1 (95% CI) | Adjusted OR1 (95% CI) | Adjusted OR1 (95% CI) | |
| Maternal Behavior | |||
| Vitamins | 1.68 (0.92, 3.05) | 1.63 (0.86, 3.08) | 1.51 (0.92, 2.48) |
| Caffeine | 1.17 (0.43, 3.20) | 1.13 (0.40, 3.18) | 1.22 (0.59, 2.53) |
| Cigarettes | 2.84 (0.94, 8.60) | 1.88 (0.58, 6.09) | 0.82 (0.30, 2.25) |
| Alcohol | 0.63 (0.33, 1.19) | 0.97 (0.49, 1.92) | 0.71 (0.40, 1.23) |
| Paternal Behavior | |||
| Cigarettes | 0.74 (0.34, 1.60) | 0.91 (0.41, 2.03) | 0.63 (0.35, 1.14) |
| Index Woman | |||
|---|---|---|---|
| Preterm | 0.41 (0.18, 0.94) | 0.47 (0.19, 1.15) | 0.98 (0.42, 2.25) |
| Low Birth Weight2 | 1.19 (0.93, 1.52) | 1.03 (0.79, 1.33) | 0.95 (0.77, 1.16) |
NOTE: In utero exposures were simultaneously included in model.
1
Model adjusted for clinical site (California/Utah), currently smoking (yes/no), age at menarche (years) and BMI (weight in kg/height in m2).
2
As lower birth is associated with increased risk of endometriosis in previous studies, birth weight entered the model so that the estimated OR/AOR confers the effect of every pound less in weight.