Skip to main content
. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Alzheimers Dement. 2013 Jan 30;9(2):99–112. doi: 10.1016/j.jalz.2012.11.005

Figure 3. The o-ELISAs detect multiple oligomeric forms of Aβ, including dimers, in soluble extracts of human brain tissue.

Figure 3

(A) NAB61/3D6B and (B) 3D6/3D6B o-ELISAs, and (C) 266/3D6B 1-x ELISA. By each method, ~80% of soluble Aβ species elute in the void volume of the Superdex 75 SEC column (i.e., F3–F5, corresponding to >70 kDa). (D) SEC elution profiles of AD-TBS extracts analyzed by WB (6E10+2G3+21F12); synthetic wt Aβ40 (2 ng) is a WB control.