Figure 3.

Experiment 3: Effects of early mPFC inactivation on subsequent performance. (A) Percent correct for control and muscimol rats during the acquisition of the first list of odor discrimination problems. Infusions were given prior to the first three training sessions (indicated by the box), after which no additional infusions were given. As in Experiment 1, temporary inactivation of the mPFC impaired learning but performance caught up to that of controls by the fifth training session. (B) Both groups of rats performed at high levels for the four asymptotic performance sessions. Error bars are not visible for some values because the SEM was smaller than the area covered by the data markers. (C) Performance during learning of the second list of conflicting odor discrimination problems. Rats that had been given muscimol infusions during the early acquisition of the first list performed better than controls. (D) Cannula placements are shown for the rats in Experiment 3 (symbols as in A). (Atlas plates were adapted from Fig. 8 in Paxinos and Watson 1998, with permission from Elsevier © 1998.)