Figure 2. Levels of Gfap promoter activity, mRNA and protein in Gfap^R236H/+ mice compared with Gfap^+/+ mice.

A comparison of the fold changes seen in Gfap promoter activity, mRNA and protein shows that all three are reflective of the other except in spinal cord and brain stem (two-way ANOVA with post-hoc Bonferroni t-test; ns, not significant; **P<0.01;*** P<0.001 compared with wild-type). Presented as an average fold-change ±1 S.D. on log 2 scale (n=3–6 per genotype, males).