Skip to main content
. Author manuscript; available in PMC: 2013 Mar 21.
Published in final edited form as: Eur J Inorg Chem. 2009 Jun 30;2009(23):3421–3430. doi: 10.1002/ejic.200900279

Table 4.

IC50 values of compounds 6-10 compared to cis-platin.

IC50(μM)[a]
Cell line Cis-platin [b] 6 7 8 9 10
Jurkat-GFP 31 97 113 76 50 23
[a]

IC50 is defined as the concentration of drug required to disrupt the plasma membrane of 50% of cell population, compared to untreated cells, after 22 hours of incubation. Cells with compromised plasma membrane were monitored using Propidium iodide (PI) and flow cytometry. Cis-platin was used as reference compound.

[b]

Ref 27.