TABLE 5.

Comparison of microarray data to quantitative reverse transcriptase–polymerase chain reaction results of selected genes in original study samples and in a new replication set in chorion between rupture site and nonrupture site

Gene symbol	Original sample set: array fold change (n = 20)	Quantitative reverse transcriptase–polymerase chain reaction
		Original sample set (n = 10)a		New replication set (n = 10)		Combined sample set (n = 20)
		Fold change	P value	Fold change	P value	Fold change	P value
ADAMTS5	−3.17	−2.81	.0239	−2.20	.0816	−2.46	.0084
BCL2	−2.26	−5.47	.0190	−2.48	NS	−3.54	.0116
CNR1	−2.26	−2.64	.0681	−2.77	.0824	−2.71	.0188
IL1RN	3.05	2.37	.0965	3.71	NS	3.03	.0480
CXCL12	−1.72	−15.60	.0009	−10.58	.0139	−12.72	.0001
IL-6	2.71	2.66	NS	13.25	.0233	6.44	.0105
CXCL14	−2.32	−6.14	.0205	−2.83	.0545	−4.01	.0037
PTGS2	2.10	1.61	NS	3.45	.0213	2.45	.0090
GNLY	−4.40	−6.27	.0050	−6.31	.0123	−6.29	.0003
PAEP	−3.93	−24.15	.0072	−30.97	.0218	−27.53	.0008
IGF2	1.57	NA	NA	−1.00	NS	−1.00	NS
IGFBP2	−2.97	−3.51	.0156	−3.29	.0323	−3.39	.0020
IGFBP4	−1.50	−2.71	.0420	−3.07	.0166	−2.90	.0022
IGFBP6	−2.30	−3.13	.0394	−1.09	NS	−1.74	.0711

NA, not available; NS, not significant.

^aOf the 20 original specimens, 10 specimens were selected randomly for quantitative reverse transcriptase–polymerase chain reaction.