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. Author manuscript; available in PMC: 2013 Mar 21.
Published in final edited form as: Am J Obstet Gynecol. 2010 May;202(5):431.e1–431.34. doi: 10.1016/j.ajog.2010.03.026

Table 11.

IPA networks of fetal genes

Network Molecules* Calculated
Score		 Focus
molecules		 Top Functions of Network
1 Angiotensin II receptor type 1, CETP, Collagen(s),F3, F7, Fibrin, Fibrinogen, FN1, HDL, HSPG2 (includes EG:3339), Ifn gamma, IFNGR1, Ige, IGF2, IgG, IL1, IL10RA, IL12 (complex), IL1R1, IL4R, Interferon alpha, Laminin, LDL, LPA, Mmp, NFkB (complex), P38 MAPK, p70 S6k, SAA@, SERPINC1, SERPINE1, Tgf beta, TIMP2, Tlr, TLR1 35 15 Cardiovascular Disease, Hematological Disease, Infectious Disease
2 AGTR1, Akt, Ap1, COL4A1, COL4A2, COL4A3, Creb, Cyclin A, Cyclin E, ERK, ERK1/2, FAK, FGF1, IGF2R, IL2, IL6R, Insulin, IRS1, MAP2K1/2, Mapk, Mek, MHC Class II, NPPA, NPR1, PDGF BB, PI3K, Pkc(s), PLC, Ras, REN, Shc, Sos, STAT, TCR, Vegf 27 12 Cardiovascular Disease, Cardiovascular System Development and Function, Embryonic Development
3 ADAM8, BDNF, C11ORF82, CARD18, CHAT, Ck2, COL4A4 (includes EG:1286), CXCL6, ELN, FSH, GBP6, GNL1, H2-Q4, Histone h3, IL1/IL6/TNF, IL17B, IL17C, IL1B, Jnk, MHC CLASS I D2D ANTIGEN, MIF, PENK, PLD3, Rac, SAA2, SCUBE1, SCUBE2, SLC14A1, SLC5A2, SLC5A4B, SLFN12L, TMEM176B, TNF, TNR, TREM3 7 4 Cancer, Cell Cycle, Cell-To-Cell Signaling and Interaction
*

Focus molecules are underlined.