. Author manuscript; available in PMC: 2013 Mar 21.

Published in final edited form as: Am J Obstet Gynecol. 2010 May;202(5):431.e1–431.34. doi: 10.1016/j.ajog.2010.03.026

Table 7.

Analysis of histologic chorioamnionitis for significantly associated SNPs

Population	Gene Code	rs#	OR¹	95% CI²		p-value
Population	Gene Code	rs#	OR¹	Lower	Upper	p-value
Maternal (Cases n=30 Controls n=464)	IL6R	rs8192282	1.82	0.87	3.80	0.110
	COL4A3	rs1882435	1.03	0.57	1.89	0.912
	LTF	rs2269435	0.95	0.54	1.67	0.845
	FGF1	rs34003	0.59	0.33	1.05	0.074
	GNB3	rs5440	0.43	0.24	0.79	0.006
	IGF1	rs5742612	0.50	0.15	1.65	0.256
	TIMP2	rs2277698	1.49	0.62	3.61	0.377

Fetal (Cases n=14 Controls n=465)	F3	rs610277	3.78	0.79	18.01	0.096
	NPR1	rs3891075	1.68	0.36	7.76	0.505
	IL6R	rs8192282	2.94	1.02	8.43	0.045
	TNR	rs2228359	1.01	0.42	2.42	0.979
	IL1B	rs1143643	1.70	0.74	3.92	0.212
	FN1	rs2304573	1.23	0.54	2.82	0.626
	IL2	rs2069772	0.22	0.03	1.59	0.133
	FGF1	rs34003	0.43	0.16	1.18	0.101
	IFNGR1	rs1887415	0.60	0.14	2.58	0.495
	IGF2	rs3213225	0.73	0.30	1.79	0.496
	COL4A1	rs16975492	0.62	0.24	1.56	0.307
	TIMP2	rs2277698	2.14	0.72	6.34	0.169

OR is the Odds Ratio for the additive genotypic model;

95% CI is the 95% confidence interval of the Odds Ratio