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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Health Phys. 2012 Oct;103(4):463–473. doi: 10.1097/HP.0b013e31826386ef

Figure 4. Longitudinal changes in minute volume (MV) is consistent with obliterative bronchiolitis observed in the C57L strains.

Figure 4

The decrease in minute volume suggests a progressive impairment in gas exchange among moribund mice in comparison to their surviving age-matched, irradiated counterparts. The decrease in MV among C57BL/6J (A) and CBA (B) strains is less robust than that among C57L/J mice (C). This is consistent with the observed pathologic injury showing complete consolidation of the alveoli with foamy-lipid laden macrophages and proteinacious edema (D). Error bars represent SEM, *p<0.05