Table 1.
Characteristics of glioma cases by family history of PBT
| Discovery study |
Replication study |
|||||
|---|---|---|---|---|---|---|
| Family history of PBT, n. (%) * |
Family history of PBT, n. (%) * |
|||||
| Variable | Yes (n=88) | No (n=1100) | P value # | Yes (n=84) | No (n=903) | P value # |
| Age, years | ||||||
| Median (range) | 45 (20–70) | 48 (18–86) | 0.34 & | 53 (26–81) | 54 (17–89) | 0.99 |
| 18–40 | 34 (38.6) | 372 (33.8) | 18 (21.4) | 215 (23.8) | ||
| 41–60 | 42 (47.7) | 553 (50.3) | 0.63 | 38 (45.3) | 397 (44.0) | 0.89 |
| ≥ 61 | 12 (13.6) | 175 (15.9) | 28 (33.3) | 291 (32.0) | ||
| Sex | 0.82 | 0.65 | ||||
| Male | 53 (60.2) | 681 (61.9) | 46 (54.8) | 520 (57.6) | ||
| Female | 35 (39.8) | 419 (38.1) | 38 (45.3) | 383 (42.4) | ||
| Histology | 0.53 | 0.94 | ||||
| GBM | 44 (50.0) | 595 (54.1) | 45 (53.6) | 480 (53.2) | ||
| non-GBM | 44 (50.0) | 505 (45.9) | 39 (46.4) | 423 (46.8) | ||
| Family history of PBT ǂ | ||||||
| No | ---- | 1100 (100) | --- | 903 (100) | ||
| 1st degree | 24 (27.3) | --- | 20 (23.8) | --- | ||
| 2nd degree | 61 (69.3) | --- | 64 (76.2) | --- | ||
| 1st and 2nd degree | 3 (0.4) | --- | 0 (0) | --- | ||
Note: PBT, primary brain tumor
*
Numbers do not add up to the column totals due to missing values.
#
By χ2 test unless otherwise noted.
&
By Wilcoxon rank sum test.