Skip to main content
. 2013 Mar 13;54(3):1881–1886. doi: 10.1167/iovs.12-10796

Figure 2.

Figure 2

Beagles genotyped for the nonsynonymous SNPs in the beagle glaucoma locus. Beagles not affected by glaucoma from two different animal supplier colonies (A, B) and from veterinary clinics (C) were genotyped for the eight nonsynonymous SNPs in the beagle glaucoma locus that segregated with disease in the beagle glaucoma colony. The key for genotype calls is shown (A). Each horizontal row represents the haplotype of one or more dogs, with number of dogs represented to the left of the row (A–C). The gene containing each variant is indicated above (A). In GPCR108, there are two nonsynonymous SNPs, GPCR108 (1) and GPCR108 (2). Minor allele frequencies for the variants are shown for the supplier colonies and clinic samples (D) with error bars representing +/− 95% CIs. The alternative allele frequency upper threshold of 10% for a putative disease allele in beagles is indicated by the dashed line (D).