Table 1.
Genes that are down-regulated in the heavy polysome fraction but not whole cell lysate of Eif4g3-silenced PCRC-1 cells.
| Gene symbol | Average fold change (n = 4) | Gene description |
|---|---|---|
| Genes down-regulated by ≥2-fold in 4 out of 4 separate experiments performed | ||
| Treml1 | 3.4 | Triggering receptor expressed on myeloid cells-like 1 |
| Anpep | 3.2 | Alanyl (membrane) aminopeptidase, CD13, Aminopeptidase N |
| Syt13 | 3.0 | Synaptotagmin XIII |
| Grtp1 | 2.8 | GH regulated TBC protein 1 |
| Ttc39b | 2.8 | Tetratricopeptide repeat domain 39B |
| Hcls1 | 2.7 | Hematopoietic cell-specific Lyn substrate 1 |
| Neurl4 | 2.7 | Neuralized homolog 4 |
| Dennd5b | 2.6 | DENN/MADD domain containing 5B |
| Genes down-regulated by ≥2-fold in 3 out of 4 separate experiments performed | ||
| Mmp3 | 3.4 | Matrix metallopeptidase |
| Fam71e1 | 3.1 | Family with sequence similarity 71, member E1 |
| Trem2 | 3.0 | Triggering receptor expressed on myeloid cells 2 |
| Fetub | 2.7 | Fetuin beta (Fetub), transcript variant 1 |
| Pcdh9 | 2.7 | Protocadherin 9 isoform 1 |
| Myom2 | 2.7 | Myomesin 2 |
| Enpp2 | 2.5 | Ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| Acacb | 2.5 | Acetyl-Coenzyme A carboxylase beta |
| Abat | 2.5 | 4-aminobutyrate aminotransferase |
| Slc38a9 | 2.5 | Solute carrier family 38, member 9 |
| Col11a2 | 2.5 | Collagen, type XI, alpha 2 |
| Lgi2 | 2.5 | Leucine-rich repeat LGI family, member 2 |
| Hkdc1 | 2.4 | Hexokinase domain containing 1 |
| Sema5a | 2.3 | Semaphorin 5A |
| Tmem87a | 2.3 | Transmembrane protein 87A |
| Ctps2 | 2.3 | Cytidine 5′-triphosphate synthase 2 |
| Mudeng | 2.2 | MU-2/AP1M2 domain containing, death-inducing |
| Mogat2 | 2.2 | Monoacylglycerol O-acyltransferase 2 |
| Rassf5 | 2.2 | Ras association (RalGDS/AF-6) domain family member 5 |
| Slit2 | 2.1 | Slit homolog 2 |
| Msln | 2.1 | Mesothelin |
| Erp44 | 2.1 | Endoplasmic reticulum protein 44 |
| Znf512b | 2.0 | Zinc finger protein 512B |
| Lrrk2 | 2.0 | Leucine-rich repeat kinase 2 |
| Sap25 | 1.9 | Sin3 associated polypeptide |
| Tcp11l2 | 1.8 | T-complex 11 (mouse) like 2 |