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. Author manuscript; available in PMC: 2013 Mar 21.
Published in final edited form as: Nat Prod Rep. 2011 Oct 6;28(12):1937–1955. doi: 10.1039/c1np00051a

Fig. 4.

Fig. 4

A. Curcumin structure showing functional groups that can serve as Michael reaction acceptors (in dotted boxes). B, C. The proposed mechanism of Michael addition of a reduced sulfhydryl and selenocysteine (Se−) moiety to the keto form of curcumin. Figure adapted from Fang et al.20 and Jung et al.91