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. Author manuscript; available in PMC: 2013 Mar 21.
Published in final edited form as: Nat Genet. 2012 Jan 29;44(3):269–276. doi: 10.1038/ng.1073

Figure 2.

Figure 2

Overall summary of basic metabolism, key constituents of the NMR-measurable serum metabolome and associated genetic loci. The green shapes represent various dietary ingredients and systemic metabolic measures reflecting human body functions. A key selection of metabolites quantified in each metabolic category is given. Red rectangles represent the newly identified genetic loci found in this work, and blue rectangles indicate loci that were previously identified. The genes are categorized by the lead trait associations given in Tables 2 and 3. In particular, ALB and FCGR2B were associated with serum cholesterol, PPP1R11 with very high VLDL measures, CPT1A with the LA/PUFA ratio, SLC25A1 with citrate, F12 with phenylalanine, TAT with tyrosine, DHDPSL with glutamine, SLC1A4 with valine and PPM1K and SLC2A4 with Fischer’s ratio.

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