Table 2. Covalent adducts formed by LdtMt2 from M. tuberculosis with the -lactam-type antibiotics imipenem and ampicillin.
| Protein construct, molecular mass (Da) | -Lactam, molecular mass (Da) | Detected mass (Da) | Mass difference (Da) |
|---|---|---|---|
| LdtMt2 periplasmic segment (34408), 40074.0 | Imipenem, 299.3 | 40374.6 | 300.6 |
| LdtMt2 BC module (149408), 28482.0 | Imipenem, 299.3 | 28780.9 | 298.9 |
| Ampicillin, 349.4 | 28831.7 | 349.7 |