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. 2013 Mar 21;9(3):e1003003. doi: 10.1371/journal.pcbi.1003003

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Short length-scale diffusion on a rough landscape (bottom) may be averaged, yielding an effective diffusion , which is obtained from simulation. Effective diffusion leads to barrier crossing attempts, where the probability of crossing is governed by the height of the long length-scale barrier ().

Inline graphic — Short length-scale diffusion on a rough landscape (bottom) may be averaged, yielding an effective diffusion , which is obtained from simulation. Effective diffusion leads to barrier crossing attempts, where the probability of crossing is governed by the height of the long length-scale barrier ().