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. 2013 Mar 21;9(3):e1002989. doi: 10.1371/journal.pcbi.1002989

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© 2013 Handel et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A) direct transmission (equation 19) and B) environmental transmission (equation 20) scenarios. We plot fitness for the three different link functions, , between within-host virus load and transmission/shedding described in the model section, i.e. , and given by equations (12), (15) and (16). Strains are sorted according to within-host fitness, with H8N4 having the best within-host fitness (i.e. lowest value of , see Table 4). We arbitrarily chose H1N1 as the reference strain, which therefore has a relative fitness of 1.

Inline graphic — A) direct transmission (equation 19) and B) environmental transmission (equation 20) scenarios. We plot fitness for the three different link functions, , between within-host virus load and transmission/shedding described in the model section, i.e. , and given by equations (12), (15) and (16). Strains are sorted according to within-host fitness, with H8N4 having the best within-host fitness (i.e. lowest value of , see Table 4). We arbitrarily chose H1N1 as the reference strain, which therefore has a relative fitness of 1.