Table 1.
Mixture decomposition (AMA-1)
| i | Titre range | πi | φi | θi |
|---|---|---|---|---|
| 1 |
-∞ < t < 10 |
0 (by definition) |
0 (by definition) |
0.247 (CI: 0.219 - 0.276) |
| 2 |
10 < t < 40 |
3.06E-5 (CI: 1.67E-8 – 5.52E-3) |
8.52E-4 (CI: 7.25E-7 – 0.0755) |
0.382 (CI: 0.349 – 0.414) |
| 3 |
40 < t < 70 |
8.26E-5 (CI: 5.59E-8 – 0.0108) |
1.02E-3 (CI: 1.17E-6 – 0.0621) |
1.68E-1 (CI: 1.44E-1 – 0.194) |
| 4 |
70 < t < 100 |
2.21E-4 (CI: 2.12E-7 – 0.0208) |
9.88E-4 (CI: 1.58E-6 – 0.0415) |
0.0600 (CI: 0.0454 – 0.0772) |
| 5 |
100 < t < 130 |
6.03E-4 (CI: 8.08E-7 – 0.0390) |
1.59E-3 (CI: 3.70E-6 – 0.0444) |
0.0356 (CI: 0.0245 – 0.0495) |
| 6 |
130 < t < 160 |
1.63E-3 (CI: 3.01E-6 – 0.0706) |
3.18E-3 (CI: 1.05E-5 – 0.0593) |
0.0263 (CI: 0.0170 –0.0383) |
| 7 |
160 < t < 190 |
4.38E-3 (CI: 1.17E-5 – 0.125) |
5.92E-3 (CI: 3.02E-5 – 0.0741) |
0.0182 (CI: 0.0107 – 0.0285) |
| 8 |
190 < t < 228 |
0.0115 (CI: 5.003E-5 – 0.209) |
9.77E-3 (CI: 7.91E-5 – 0.0831) |
0.0113 (CI: 5.61E-3 – 0.0198) |
| 9 |
228 < t < 258 |
0.0300 (CI: 1.97E-4 – 0.332) |
0.0281 (CI: 3.87E-4 – 0.156) |
0.0124 (CI: 6.43E-3–0.0213) |
| 10 |
258 < t < 541 |
0.0748 (CI: 8.63E-4 – 0.485) |
0.0657 (CI: 1.70E-3 – 0.244) |
0.0113 (CI: 5.57E-3 – 0.0198) |
| 11 |
541 < t < 710 |
0.174 (CI: 3.68E-3 – 0.644) |
0.163 (CI: 0.0100 – 0.418) |
0.0112 (CI: 5.60E-3 – 0.0197) |
| 12 |
710 < t < 1547 |
0.352 (CI: 0.0156 – 0.801) |
0.384 (CI: 0.0838 – 0.794) |
0.0113 (CI: 5.60E-3 – 0.0198) |
| 13 | 1547 < t < 1730 | 0.577 (CI: 0.0415 – 0.942) | 0.161 (CI: 0.0187 – 0.818) | 1.95E-3 (CI: 2.88E-4 – 6.45E-3) |
Medians and Bayesian Credible Intervals (CI, 2.5th to 97.5th percentile) of the estimated seroprevalence πi in each titre range i and the probabilities φi and θi that a seropositive or -negative person, respectively, has an AMA-1 titre in range i. The overall seroprevalence π was 0.0169 (CI: 6.24E-4 – 0.0888). The titres of 40 unexposed individuals living in Yogyakarta served as negative control group.