Table 2. Sample size calculations for superiority trials.

Control treatment Success Rate	Test treatment Success Rate	Power	N Per Group
0.6	0.7	0.80	356
0.6	0.7	0.85	407
0.6	0.7	0.90	477
0.6	0.7	0.95	589
0.6	0.8	0.80	82
0.6	0.8	0.85	93
0.6	0.8	0.90	109
0.6	0.8	0.95	134
0.6	0.9	0.80	32
0.6	0.9	0.85	36
0.6	0.9	0.90	42
0.6	0.9	0.95	52
0.65	0.7	0.80	1377
0.65	0.7	0.85	1575
0.65	0.7	0.90	1842
0.65	0.7	0.95	2278
0.65	0.8	0.80	138
0.65	0.8	0.85	158
0.65	0.8	0.90	185
0.65	0.8	0.95	228
0.65	0.9	0.80	43
0.65	0.9	0.85	49
0.65	0.9	0.90	57
0.65	0.9	0.95	70
0.7	0.8	0.80	294
0.7	0.8	0.85	336
0.7	0.8	0.90	392
0.7	0.8	0.95	485
0.75	0.8	0.80	1094
0.75	0.8	0.85	1251
0.75	0.8	0.90	1464
0.75	0.8	0.95	1810
0.75	0.9	0.80	100
0.75	0.9	0.85	114
0.75	0.9	0.90	133
0.75	0.9	0.95	164
0.8	0.9	0.80	199
0.8	0.9	0.85	228
0.8	0.9	0.90	266

Efficacy in the reference arm from 60–80%, delta 10–30%, alpha error 0.05, power 80–95%.