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. 2013 Mar 5;13:56. doi: 10.1186/1472-6882-13-56

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Copyright ©2013 Salama et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Representative images showing the macroscopic appearances of livers sampled from rats in different experimental groups. (12A) The liver of a control rat exhibiting a regular smooth surface. (12B) The liver of a hepatotoxic rat depicting numerous irregular whitish micro- and macronodules on its surface and a large area of ductular cholangiocellular proliferation (arrow) embedded within fibrotic areas. (12C) The liver of a hepatoprotected rat treated with Silymarin showing a normal smooth surface. (12D) The liver of a rat treated with low dose CLRE with a nearly smooth surface with few granules (arrow head). (12E) The liver of a rat treated with high dose CLRE with a normal smooth surface.