Table 1.

Clinical features of the Patients with DMNT3A mutations

No	Age	sex	FAB	Cytogenetics	WBC X10^9/L	CD33+/CD34+	DNMT3A	Chemo-response	result
7	65	F	M1	normal	36.6	6%/92%	2645 G > A	CR	Dead(12 M)
19	72	M	M2	normal	57.2	99%/32%	914 G > A	No	Dead(6 M)
22	55	M	M5	normal	112.9	99%/16%	2645 G > A	CR	Alive(SCT)
38	58	F	M5	t(6;9)	12.1	56%/55%	2096 G > A	CR	Dead(10 M)
40	56	F	M2	inv(9)	15	20%/82%	30 bp del 2502-2531	CR	Dead(SCT)
47	31	F	M5	del(13)	1.5	95%/27%	2501 C > T	N0	Dead(3 M)
48	20	F	M5	normal	30.4	4.5%/71%	2501 C > T	N0	Dead(3 M)
53	53	F	M3	t(4;17)	7.9	82%/1.6%	55 C > T	CR	Alive
56	54	F	M5	normal	2.19	95%/28%	2202 C > A	CR	Relapse(6 M)
68	52	M	M5	normal	28.8	97%/42%	2644 C > T	No	Dead(6 M)
77	76	M	M5	normal	67	No	2645 G > A Arg882His	CR	Dead(13 M)
89	76	M	M1	normal	17.3	CD13 CD34	1906 G > A 2191 T > C	NR	Dead(3 M)
94	61	F	M5	normal	132	CD7CD13CD33	2141C > G	NO	Dead(1 M)
100	46	M	M5	normal	4.5	CD13CD34	1792C > T 2375 G > A	NR	Dead(1 M)

CR Complete remission, No no chemotherapy, NR not remission, M month.