Figure 2. Gain adaptation and recovery.

A. Raw data from an example subject. Primary saccade gains (black dots) are plotted versus trial numbers for each ISS condition, with 0.0-ISS at top, down to 0.1 at bottom. Red dashed lines indicate the final target position, and purple traces are robust lowess smooths, this color indicates the example subject’s data, also in purple, at right (subject 5), in B and C. Gray shaded regions indicate those used to calculate adaptation and recovery magnitudes plotted in B, and C. For the details of this procedure, see Methods. Briefly, adaptation was calculated by the difference between the means of the final 50 trials of baseline and adapt phase using the Tukey-Kramer method after an ANOVA. B. Magnitude of adaptation across and within subjects. Gray boxes and dark gray line segments in background represent across-subjects adaptation, while colored boxes and white line-segments represent individual subject adaptation (mean ±95% CI: Confidence Interval; box colors correspond to subjects as indicated in legend). Dashed grey line represents 0 adaptation, and may be used to determine significance by comparison with group or individual CIs (non-overlapping meaning significant adaptation). Red dashed lines represent ISS values (in gain units), and grey italic text above axis indicates mean across-subjects adaptation magnitude. We have also indicated those cases in which the ISS value was greater than the subject’s baseline variability (σ_b) in that session. C. Magnitude of recovery across and within subjects. Conventions as in B, except red dashed line-segments now indicate (sign-reversed) adaptation magnitude as calculated above (in A) and grey italic text above axis now indicates the magnitude of recovery across subjects. Black dashed line represents 0 recovery, and may again be used to determine significance by comparison with a CI of interest.